Analysis of the packaging problems of the most pop

Analysis of common drug packaging problems

with the development of market economy, the drug market has undergone profound changes. The outer packaging of drugs is becoming more and more exquisite and light It greatly facilitates the clinical and consumer drug needs. However, in our daily work, we often see that the plastic medicine bottles that pack drugs are not tightly sealed, and the sugar coated tablets inside produce discoloration, deliquescence, caking and mildew; Or because the labels of plastic medicine bottles are not pasted firmly, fall off and lost, resulting in the unidentifiable tablets, resulting in waste of drug resources and economic losses. 1. Problem generation and raising

1 Our hospital is a comprehensive hospital in East China and the leader of Anhui health industry. It undertakes heavy medical, teaching and research tasks. In 1999, the amount of drugs sold in the outpatient pharmacy alone reached more than 32 million yuan Pharmacy windows need to allocate a large number of Western medicine prescriptions every day. The quality of drugs is related to the safety of patients and the improvement of hospital medical quality

1. 2 the Pharmacopoeia clearly stipulates that drugs should be stored in closed Brown dry glass bottles; There are strict requirements on the temperature and humidity of storage. The vast majority of plastic processing enterprises mainly rely on domestic manufacturing equipment. In order to save costs and facilitate transportation, manufacturers have changed the packaging of drugs (tablets) to plastic bottles

1. 3. For plastic bottle packaging, because of its poor airtightness, over time, the tablets inside are often prone to discoloration, deliquescence, caking, mildew and other phenomena. For example, the specification of "antailol tablets" produced by Shanghai Huanghe pharmaceutical factory is 25 mg × 100 tablets, which has not been completely solved for many years

1. 4. The plastic bottle has smooth outer wall and poor adhesion; After several twists and turns, the labels of the drugs that left the factory soon have fallen off in the hands of the users. Due to the failure to stick it in time, it is difficult to confirm what medicine is in the plastic bottle for a long time, so it has to be scrapped. Over time, the economic losses caused are quite amazing. However, just because the drug packaging labels are not pasted firmly, fall off and lost, a large number of drug resources are wasted and lost, which is painful. Practical work has proved that the drugs packaged in brown glass bottles rarely produce the above phenomena

1. According to rough statistics, in just one month, the hospital found that the drugs being used were packed in plastic bottles and the labels were not firmly adhered: phenformin hydrochloride tablets (Jiangtangling) produced by Jintan pharmaceutical factory in Jiangsu Province, with a specification of 25mg × 100 tablets, batch number, unit price 3130 yuan. More than 80 bottles were discarded at one time because the labels fell off and were lost. The specification of propafenone hydrochloride tablets (propafenone) produced by Changle pharmaceutical factory of Shanghai Pharmaceutical Company is 50mg × 100 tablets, batch number 990201; Propranolol hydrochloride (propranolol tablets) produced by the third pharmaceutical factory in Yancheng, Jiangsu, China has a specification of 10 mg × 100 tablets, batch number 990609; The specification of mexil hydrochloride tablets (slow heart rate tablets) produced by Shanghai Jiufu Pharmaceutical Co., Ltd. is 50 mg × 100 tablets, batch number 990801; The "Hericium erinaceus tablets" produced by the state-run Rugao biochemical pharmaceutical factory are packed in 100 pieces, batch number 990317; The specification of hydroxyzine hydrochloride tablets (antailar tablets) produced by Shanghai Jiufu Pharmaceutical Co., Ltd. (the former Shanghai Huanghe pharmaceutical factory) is 25mg × 100 tablets, batch number 980822f; Furan thiamine tablets, specification 25 mg × 100 tablets, batch number 990801e; Nicotinic acid tablet, specification 50 mg × 100 pieces, batch number 980721; 100 pieces of compound rutin tablets, batch No. 990201; The specification of dibazole tablets produced by Dafeng Jiangsu Fangqiang pharmaceutical factory in China is 10mg × 100 tablets, batch number 990914; Methimazole tablets (tabazole), specification 5mg × 100 tablets, batch number 990907. Shark liver alcohol tablets produced by Jiangsu penghe Pharmaceutical Co., Ltd. (the former Yixing pharmaceutical factory), with a specification of 50 mg × 100 tablets, batch number 990828; Acetylsalicylic acid enteric coated tablets produced by Nanjing second pharmaceutical factory 25 mg × 100 pieces, batch number; Thyroid tablets produced by Shanghai Great Wall biochemical pharmaceutical factory 40 mg × 100 tablets, batch number 990902; The specification of berberine hydrochloride tablets (Berberine Tablets) produced by Sino foreign joint venture Shanghai famasei Pharmaceutical Co., Ltd. is 011 G × 100 pieces, batch No. 990502. Among them, the specification of clotrimazole tablets produced by Shanghai simpas Pharmaceutical Co., Ltd. is 0125 G × 100 pieces, batch number 980621; Phenytoin sodium tablets specification 100 mg × 100 tablets, batch number 990622; The specification of LuoNeizhi tablets (spironolactone) produced by Shanghai Fuda Pharmaceutical Co., Ltd. is 20 mg × 100 tablets, batch No. 990901, the specification of estazolam tablets (sullain) produced by Shanghai integrated pharmaceutical factory in China is 1 mg × 100 tablets, batch number 990601; Metoclopramide (metoclopramide tablets) produced by Jiangsu Danyang Pharmaceutical Co., Ltd. 5 mg × 100 tablets with batch number of 000212, the labels of these drugs fell off particularly seriously, and almost most of them had to be re pasted. The specification of nifedipine tablets (nifedipine) produced by Shanghai Tianping pharmaceutical factory is 10 mg × 100 pieces, batch No. 991102e, are of good quality. They are also packed in plastic bottles. Over the years, labels have hardly fallen off or lost

the above list is only the drugs produced by some manufacturers that are easy to lose labels when packed in plastic bottles. It is not complete, and there are many others, which are not listed one by one

2 measures and suggestions

2 The fluctuation (electro-hydraulic servo and hydraulic) and control accuracy (electromagnetic resonance) of the experimental machine are mainly investigated. Drug manufacturers should firmly establish the awareness of product quality first and strictly control the quality of drug production and packaging. Because the internal quality of drugs is directly related to the health of the people, the economic interests of distribution and use units and the reputation of manufacturers

2. It is suggested that all drug manufacturers study and improve packaging, promote experience, increase the tightness and moisture resistance of plastic bottle mouth and the firmness of drug label adhesion, and strictly control product quality

2. 3. All distribution and use units should strictly implement internal management, strengthen the hearts of employees and the spirit of ownership of caring for the collective, caring for public property and loving their jobs, and solve problems in a timely manner when they are found, so as to reduce unnecessary losses caused by both parties' unswerving implementation of sustainable development and operation strategies in the production field. Fundamentally put an end to the economic losses caused by drug packaging problems, so that valuable drug resources can truly benefit the people's health cause

(Wei Jingdong, the First Affiliated Hospital of Anhui Medical University, source: Chinese Journal of Medicine)